Don’t assume early detection is worthwhile
‘Screening for neuroblastoma illustrates how easily one can fall into the trap of assuming that because a disease can be detected early, screening must be worthwhile . . . The two studies demonstrate how neuroblastoma screening was not only worthless, but led to “over-diagnosis” and must have identified tumours that would have spontaneously regressed. Both studies mentioned children in the screened group suffering severe complications due to the treatment . . . Hopefully these lessons will be learned when considering the implementation of other screening programmes – for example screening for prostate cancer.’
Morris JK. Screening for neuroblastoma in children. Journal of Medical Screening 2002;9:56.
Read more in: Lessons from neuroblastoma screening.