2-12 Single studies can be misleading

A single comparison of treatments rarely provides conclusive evidence and results are often available from other comparisons of the same treatments. These other comparisons may have different results or may help to provide more reliable and precise estimates of the effects of treatments.

The results of single comparisons of treatments can be misleading. Consider all of the relevant fair comparisons.

Browse by Key Concept

Back to Learning Resources home

Filter these resources:

Clear Filters


Cartoon and blog about how poorly performed systematic reviews and meta-analyses may misrepresent the truth.


Forest Plot Trilogy

Synthesising the results of similar but separate fair comparisons (meta-analysis) may help by yielding statistically more reliable estimates

Book cover

Is one study ever enough?

The simple answer is ‘hardly ever’. Very seldom will one fair treatment comparison yield sufficiently reliable evidence on which to […]

| 1 Comment

No Resources Found

Try clearing your filters or selecting different ones.