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University of Western Australia: Bias Minimisation, randomisation and blinding
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University of Western Australia’s explanation of why random allocation to comparison groups and blinding (if possible) are important.
Key Concepts addressed:- 2-2 比較群は同等でなければなりません
- 2-5 自分がどの治療を受けたのかを知るべきではありません
- 2-7 すべて経過観察が必要です
- 2-8 関連する公正な比較はすべて検討してください
- 2-17 「統計学的有意性」と「重要性」を混同しないでください
- 3-1 測定された転帰はあなたにとって重要ですか?
Details
Bias minimisation; Study Methodology
- Randomisation eliminates investigator bias in allocating patients to different treatment arms.
- Blinding can avoid bias due to patient or observer knowledge of treatment allocation. Blinding can be through use of placebo or sham treatment. In a single blind study, only the patient or observer is unaware of the treatment allocation.