The interpretation of clinical trials
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Peter Greenberg’s 9-minute read on the interpretation of clinical trials.
Key Concepts addressed:- 1-6 専門家の意見が必ずしも正しいとは限らない
- 2-2 比較群は同等でなければなりません
- 2-5 自分がどの治療を受けたのかを知るべきではありません
- 2-7 すべて経過観察が必要です
- 2-8 関連する公正な比較はすべて検討してください
- 2-17 「統計学的有意性」と「重要性」を混同しないでください
- 2-18 「エビデンスがない」と「効果がない」を混同しないでください
- 2-14 効果の平均的測定は誤解を招く可能性があります
Details
Summary
Clinical trials are the foundations of evidence-based treatments. Trials must be critically appraised to confirm the validity of conclusions. Further analysis is required to show if the results from the trial, where patients are carefully selected and followed up in detail, can be extrapolated to other patients and different settings. Data from additional sources including other trials, meta-analyses, practice guidelines, trusted opinions and clinical experiences modify prescribing practices.