MMR: the facts in the case of Dr Andrew Wakefield
This 15-page cartoon explains the events surrounding the MMR controversy, and provides links to the relevant evidence.Key Concepts addressed:
- 1-2 体験談は信憑性のないエビデンス
- 1-6 専門家の意見が必ずしも正しいとは限らない
- 1-7 利益相反に気を付けること
- 2-1 治療効果を特定するためには比較が必要です
- 2-11 公正な比較および転帰はすべて報告する必要があります
- 2-15 人数または転帰イベントの少ない公正な比較は誤解を招く可能性があります
This is a wonderful 15-page cartoon by Darryl Cunningham explaining the events that led to the disastrous loss of confidence in the Measles-Mumps-Rubella (MMR) combined vaccine.
It focuses on the fraud perpetrated by Dr Andrew Wakefield and the failure of the media to investigate the conflict of interest that lay behind his claims.
The cartoon covers:
- recent trends in anti-science sentiment
- Wakefield’s unsubstantiated theory that the MMR vaccine causes autism
- his misrepresentation of the findings of his own research to undermine confidence in MMR
- the global health scare around MMR and autism
- subsequent outbreaks of measles in several countries.
- he was initially hired by a medical negligence lawyer to find evidence that the MMR vaccine was harmful
- he filed a patent for a single measles vaccine in direct competition with MMR
- he conducted unethical research on children
- he was eventually struck off by the General Medical Council.
The role of the media in this story is also dealt with:
- their unquestioning acceptance of Wakefield’s claims
- sensationalising the story
- failure to acknowledge the overwhelming evidence from high quality studies that contradicted his theory
- their use of writers with little knowledge of science and medical research.
- Demicheli V, Rivetti A, Debalini MG, Di Pietrantonj C. Vaccines for measles, mumps and rubella in children. Cochrane Database of Systematic Reviews 2012, Issue 2. Art. No.: CD004407. DOI: 10.1002/14651858.CD004407.pub3